After administering Ceftriaxone Injection, monitor patients for allergic reactions such as rash, swelling, or difficulty breathing. Observe for signs of anaphylaxis, including hypotension and rapid heartbeat. Watch for gastrointestinal symptoms like nausea, vomiting, or diarrhea. Regularly check for pain, redness, or swelling at the injection site. Monitor liver and kidney function through lab tests, especially in long-term use. Look for signs of Clostridium difficile-associated diarrhea. Assess for neurological symptoms like seizures in high doses. Ensure hydration to prevent kidney complications. Immediate medical attention is required if severe side effects occur post Ceftriaxone Injection administration.