Ivermectin is a widely used antiparasitic medication that has proven effective in treating various parasitic infections in humans. Originally developed as a veterinary drug, it was later approved for human use in the 1980s and has since become a critical tool in combating several debilitating diseases. Ivermectin Tablet is particularly effective against strongyloidiasis and onchocerciasis (river blindness), both of which are caused by parasitic worms.

Mechanism of Action: Ivermectin works by binding to specific chloride channels in the nerve and muscle cells of parasites, leading to paralysis and death of the organism. This action disrupts the parasites’ ability to move and feed, ultimately eliminating them from the host’s body.

Indications: The primary uses of ivermectin include treating strongyloidiasis, which can cause gastrointestinal symptoms such as abdominal pain and diarrhea, and onchocerciasis, which can lead to severe itching and vision loss. Additionally, ivermectin is effective against other infections such as ascariasis, trichuriasis, cutaneous larva migrans, and lice infestations. It is also used topically to treat conditions like scabies and rosacea.

Dosage and Administration: Ivermectin is typically administered as a single oral dose, with the dosage depending on the specific infection being treated and the patient’s weight. For example, for strongyloidiasis, the recommended dose is **200 micrograms per kilogram** of body weight.

Safety and Side Effects: Ivermectin is generally well-tolerated; however, some patients may experience side effects such as nausea, dizziness, or skin rash. It is crucial to use ivermectin under medical supervision to avoid potential drug interactions and ensure appropriate treatment.

Overall, ivermectin remains an essential medication in global health initiatives aimed at controlling parasitic diseases, particularly in low- and middle-income countries where these infections are prevalent.